Vit C promotes collagen synthesis. When vitamin deficiency occurs, collagen cannot be synthesized, resulting in dysfunction of cellular connections. How do collagen and Vit C work?
Collagen is a water-insoluble protein found in various parts of the body. It must uncoil the three-strand helical structure that holds it together to form a soluble gelatin to dissolve easily in water.
Gelatin is a long chain of molecules made up of amino acids. It differs from other proteins in that it contains a large proportion of hydrophilic amino acids. In particular, there are two amino acids with hydroxyl groups, hydroxyproline and hydroxylysine. This is the "characteristic" amino acid of collagen.
The body synthesizes these two characteristic amino acids by taking lysine and proline from food and adding a hydroxyl group to them to become hydroxyproline and hydroxylysine. The hydroxylation of proline during synthesis requires active vitamin C.
Therefore, the lack of active VC collagen can not be synthesized normally, resulting in cell connection disorder and collagen synthesis disorder in the body.
Anything that needs collagen -- bones, tendons, skin, blood vessels -- can have problems. Blood vessels are in big trouble - because the walls of blood vessels are connective tissue, which is also made of collagen. Blood vessel maintenance problems, from subcutaneous bleeding to internal bleeding, are "scurvy" symptoms.
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